1.1

1.1.2

This patch version makes the following corrections and clarifications:

  • Adds the intended ChromosomeLocation prefix to the Computed Identifiers table.

  • Revises the Cytoband information model to align with ISCN conventions.

  • Updates the Cytoband regex to match the specified model.

1.1.1

This patch version makes the following corrections and clarifications:

  • Correct styling / indexing of CytobandLocation in restructuredText to match the current Schema and ER Diagram.

  • Remove erroneous bracket notation after CURIE from the locations attribute in the Allele information model.

  • Added citation for sha512t24u and truncated digest collision analysis.

  • Revised Note in inter-residue design decision to acknowledge community terms.

1.1.0

1.1.0 is the second release of VRS.

New classes

  • ChromosomeLocation: A region of a chromosome specified by species and name using cytogenetic naming conventions

  • CytobandInterval: A contiguous region specified by chromosomal bands features.

  • Haplotype: A set of zero or more Alleles.

  • VariationSet: A set of Variation objects.

Other data model changes

  • Interval was renamed to SequenceInterval. Interval was an internal class that was never instantiated, so this change should not be visible to users.

Documentation changes

  • Added relationships to describe how VRS relates to other standards.

  • Updated Normalization to clarify handling of reference alleles and generalize terminology to apply to all VRS objects.

  • Updated current and future schema diagrams.

  • Included a discussion of the release-cycle.