Systemic Variation

VRS currently covers many classes of variation that are defined on multiple molecules in the context of a system, e.g. a genome, sample, or homologous chromosomes.

Collectively, these types of variation are called systemic variation.

Trial Use

May change in future releases. See Maturity Model.

Abstract Class — not instantiated directly; concrete subclasses inherit its attributes.

Sealed — SystemicVariation has a closed, exhaustive set of concrete subclasses; every one is listed below. No other subclass is permitted, and a conforming instance must be exactly one of these types.

Computational Definition

A Variation of multiple molecules in the context of a system, e.g. a genome, sample, or homologous chromosomes.

Information Model

This class must match one of the following:

• Copy Number Change

• Copy Number Count

Inherits: Variation

Subclasses: Copy Number Change, Copy Number Count